児童病棟でパルボウイルスB19が流行した

D Pillay¹, G Patou, S Hurt

¹Division of Communicable Diseases, Royal Free Hospital and School of Medicine, London, UK.

Lancet (London, England)

|January 11, 1992

まとめ

パルボウイルスB19の流行は,脆弱な集団にリスクをもたらします. 病院での疫病発生時,感染制御対策が実施されましたが,感染拡大を制限する効果は不明です.

科学分野:

ウイルス学ウイルス学ウイルス学
感染症感染症は感染症です.
病院疫学病院疫学について

背景:

パルボウイルスB19感染は,妊娠中の女性,血液溶解性貧血の患者,免疫低下者にとって重大なリスクをもたらす.
病院でのアウトブレイクの管理には,患者の保護と不可欠な医療サービスの維持のバランスをとる必要があります.

研究の目的:

小児科で発生したパルボウイルスB19の発生を調査する.
疫病発生時に実施された感染対策の評価を図る.

主な方法:

58人の病院スタッフのスクリーニングで,パルボウイルスB19マーカー (血清IgMおよびウイルス性血症) を検出した.
感染感受性の高いスタッフおよび免疫不全の患者における感染発達の評価.
隔離,免疫グロブリン療法,病棟制限の実施.

主要な成果:

6人の感受性の高い男性スタッフのうち4人,24人の感受性の高い女性スタッフのうち6人が感染した (p=0.05).
11人の感染した成人のうち1人,免疫力が低下した12人の患者のうち2人は無症状でした.
実施された措置と感染拡大の制限との明確な相関は確立されなかった.

結論:

パルボウイルスB19は,病院で無症状に感染することがあります.
このアウトブレイク中の特定の感染制御介入の有効性は,決定的に決定することができなかった.

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