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Updated: Jun 21, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

初等子宮頸がんにおけるクローナルp53変異:ヒトパピローマウイルス陰性腫瘍との関連

T Crook1, D Wrede, J A Tidy

  • 1Ludwig Institute for Cancer Research, St Mary's Hospital Medical School, London, UK.

Lancet (London, England)
|May 2, 1992
PubMed
まとめ

ヒトパピローマウイルス (HPV) 感染症は,子宮頸がんにおけるp53遺伝子変異と逆相関しています. HPV陽性腫瘍は,主に野生型のp53を示しており,腫瘍抑制遺伝子の無活性化の異なるメカニズムを示唆しています.

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