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授乳乳児における亜鉛サプリメント
P A Walravens1, A Chakar, R Mokni
1Unité 1, INSERM, Paris, France.
Lancet (London, England)
|September 19, 1992
まとめ
亜鉛サプリメントは,成長が鈍っている乳児の線形成長と体重増加を大幅に改善しました. これは,亜鉛の摂取量が不十分であることが,一部の母乳の乳児の成長に寄与していることを示唆している.
科学分野:
- 小児科は小児科です.
- 栄養科学とは,栄養科学である.
- 人間の成長と発展
背景:
- 成長障害は,世界中で母乳で育った乳児に共通しています.
- この現象における栄養素亜鉛欠乏の役割については,さらなる調査が必要である.
研究 の 目的:
- 亜鉛のサプリメントが,成長が鈍っている乳児の成長パラメータを改善できるかどうかを判断する.
- 亜鉛欠乏が乳児の成長速度に与える影響を評価する.
主な方法:
- ランダム化,プラセボ対照試験で,4~9ヶ月の乳児57人を対象に実施した.
- 乳児は1日5mgの亜鉛または3ヶ月間プラセボを投与されました.
- 成長パラメータ (身長,体重,Zスコア) は,サプリメント摂取前と後の測定を行った.
主要な成果:
- 亜鉛サプリメントは,プラセボと比較して,年齢対長さのZスコアが有意に増加しました (+0.21 vs -0.13,p=0.029).
- 亜鉛 (6.0cm対4.6cm,p=0.02) を投与した男の子の線形成長がより顕著であった.
- 亜鉛群では体重増加が著しく高かった (1.64kg vs 1.28kg,p=0.047).
結論:
- 亜鉛サプリメントは,成長が鈍っている乳児の線形成長と体重増加を効果的に改善することができます.
- 十分な亜鉛摂取量が不足すると,4ヶ月以上母乳で育った乳児の成長速度が低下する可能性があります.
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