中国中部でアルベオラエキノココシスの大きな焦点
P S Craig1, L Deshan, C N MacPherson
1Department of Biological Sciences, University of Salford, UK.
Lancet (London, England)
|October 3, 1992
まとめ
深刻な寄生虫性疾患であるヒト胞性エキノココシス (AE) は,中国農村部で高い割合で発見されました. 集団スクリーニングでは,5%の流行が判明し,流行地域におけるより良い衛生と犬との接触制御の必要性を強調しました.
科学分野:
- 動物性感染症は動物性感染症です.
- 寄生虫学とは,寄生虫学である.
- 公衆衛生は公衆衛生である.
背景:
- ヒト胞性エチノコッコシス (AE) は, Echinococcus multilocularis.によって引き起こされる珍しいが重症な寄生動物性ゾオノシスです.
- 伝播は一般的に北緯度に限られており,中国中部ではほとんど研究されていない.
- 以前の血清検査は,研究地域における潜在的宿主性を示した.
研究 の 目的:
- 中国の甘肅省の農村地域における肝臓AEの流行を決定する.
- AE検出のための血清学と組み合わせた質量超音波スキャンの有効性を調査する.
- 研究対象集団におけるAEの危険因子と伝播パターンを特定する.
主な方法:
- 3つの地方自治体の1312人の住民の集団超音波スクリーニング.
- 診断を確認するための血清検査.
- 罹患率と危険因子を評価するための予備血清検査とフォローアップ研究.
主要な成果:
- 集団スクリーニングと血清学を使用して,肝臓AEの5% (65/1312) の有病率が診断されました.
- 血清陽性の割合は,村ごとに (0~20%) 大きく異なっていた.
- 31歳から50歳の女性および個人は,感染のリスクが高く,おそらく犬との接触に関連していることが示されました.
結論:
- この研究は,中国中部における重要な公衆衛生問題を示す,記録されている最も高いAE流行率の1つを特定しました.
- 超音波と血清検査の併用は,流行地域における集団スクリーニングに有効であることが示されました.
- 高い罹患率は,ネズミと犬を含む半国内感染サイクルによる可能性があり,貧困や衛生状態の不良により悪化しています.
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