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Updated: Jun 24, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

CD4+CD8+細胞に微分化される前の前駆体チモサイトのネガティブ・セレクション

Y Takahama1, E W Shores, A Singer

  • 1Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

Science (New York, N.Y.)
|October 23, 1992
PubMed
まとめ

免疫系の発達に不可欠なT細胞の選択は,これまで考えられていたよりも早く起こる可能性があります. 研究によると,T細胞受容体 (TCR) 信号伝達は,CD4+CD8+段階より前にT細胞の成熟を停止させ,T細胞レパートリー形成に影響を及ぼします.

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