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Updated: Jul 17, 2026
07:16
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
アナル内皮内腫瘍症:多焦点疾患のプロセスの一部である
J H Scholefield1, W G Hickson, J H Smith
1Department of Surgery, Northern General Hospital, Sheffield, UK.
Lancet (London, England)
|November 21, 1992
まとめ
高度子宮頸内膜内腫瘍症 (CIN) を患っている女性は,内膜内腫瘍症 (AIN) のリスクが高くなります. 多焦点性生殖器新生病は,門の関与のリスクを大幅に増加させ,門スクリーニングの必要性を強調します.
科学分野:
- 婦人科腫瘍学 婦人科腫瘍学
- アノレクトル病理学
- ウイルス腫瘍学 ウイルス腫瘍学
背景:
- 侵襲性アノゲニタルがんはヒトパピローマウイルス (HPV) タイプ16と関連しています.
- 生殖器内皮質内腫瘍症は多焦点性であり得るが,これらの症例における内腫瘍症の有病率は十分に研究されていない.
研究 の 目的:
- 高度度子宮頸内膜内腫瘍症 (CIN) の女性は,内膜内腫瘍症 (AIN) のリスクが高くなるという仮説を検証する.
- 性器管内皮質内腫瘍症の女性におけるAINの罹患率を決定する.
主な方法:
- 頸部内皮内腫瘍III度 (n=152) を有する女性における内生検のヒストロジック検査を,対照群 (n=50) と比較した.
- アナルバイオプシーサンプルでのHPV 16DNA検査.
- マルチフォーカル内皮内腫瘍 (子宮頸,ヴァルバ,ヴァギナ) の評価
主要な成果:
- CIN IIIの女性の19%は,AIN.の組織学的証拠を持っていた.
- 多焦点性生殖器内膜内腫瘍症の女性の57%は門病変があり,子宮頸部病変のみの7%と比較した.
- HPV 16 DNAは,研究グループからの内生検サンプルの51%で検出されました.
結論:
- 高度子宮頸部内皮性腫瘍症を有する女性は,内皮性腫瘍症のリスクが高くなります.
- 多焦点性生殖器内皮質腫瘍症は,内皮質腫瘍症の有意に高い罹患率と関連しています.
- 性器内皮内腫瘍症の女性の管理における内検査の役割に関するさらなる調査は正当化されています.
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