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高親和性IgE受容体の活性化により,SRCタンパク質に関連するチロシンキナーゼが活性化されます

E Eiseman1, J B Bolen

  • 1Department of Molecular Biology, Bristol-Myers Squibb Pharmaceutical, Research Institute, Princeton, New Jersey 08543-4000.

Nature
|January 2, 1992
PubMed
まとめ

高親和性IgE受容体 (Fc epsilon RI) は,p56lynおよびp62c-yesなどの異なるsrcタンパク質に関連するチロシンタンパク質キナーゼ (TPK) を活性化させ,受容体に結合することでアレルギー反応を誘発する.

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