視覚皮質の内在的な水平接続の選択は,相関するニューロン活動によって行われる
1Max-Planck-Institut für Hirnforschung, Frankfurt am Main, Federal Republic of Germany.
まとめ
視覚体験は脳の回路を形成する. ストラビズムの子猫では,視覚皮質の接続は,相関する活動を持つ細胞を好み,経験依存の回路選択を示した.
科学分野:
- 神経科学は神経科学である.
- 発達神経科学とは
- ビジュアルシステム ビジュアルシステム
背景:
- 視野皮質の長距離軸索付近線は,細胞群を結ぶ.
- これらの接続は,産後,剪定を通して精製されます.
- 回路特異性における相関神経活動の役割は不明である.
研究 の 目的:
- 関連神経活動が視覚野の接続の選択的安定化を導くかどうかを調査する.
- 視覚体験が皮質内回路の発達に与える影響を判断する.
主な方法:
- 子猫は,腸内視線信号相関を妨害するために,誘発された視線乱れで育てられました.
- 17領域のニューラル活動と接続パターンを分析した.
主要な成果:
- 17領域の細胞群は,主に1つの目からの入力によって駆動されていました.
- タンゲンシャルな皮質内繊維は,同じ目によって活性化された細胞群を好ましく結びつけます.
結論:
- 視覚回路の開発は,視覚体験に依存しています.
- 神経活動の相関は,シナプス接続の重要な選択基準として機能します.
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