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In Vivo Modeling of the Morbid Human Genome using Danio rerio
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性線維症の動物モデルが,遺伝子ターゲティングによって作られる

J N Snouwaert1, K K Brigman, A M Latour

  • 1Department of Medicine, University of North Carolina, Chapel Hill 27599-7020.

Science (New York, N.Y.)
|August 21, 1992
PubMed
まとめ

研究者らは,システィック・フィブロシス・トランスメブラン伝導性調節器 (CFTR) 遺伝子を破壊することによって,システィック・フィブロシス・マウスモデルを作成した. これらのマウスは,腸内閉塞と成長不全を含むヒトCFTR疾患の重要な特徴を示しており,この状態を研究するのに有用であることが証明されています.

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