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Updated: May 5, 2026

A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl
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A Colorimetric Assay that Specifically Measures Granzyme B Proteolytic Activity: Hydrolysis of Boc-Ala-Ala-Asp-S-Bzl

Published on: November 28, 2014

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サイト毒性は,サイトリシンとグラン酵素Aの両方を発現するラットベースフェリック白血病細胞による標的DNA分解によるサイト毒性です

J W Shiver1, L Su, P A Henkart

  • 1National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

Cell
|October 16, 1992
PubMed
まとめ

研究者はネズミのマスト細胞を細胞毒性タンパク質を発現させるように設計し,その強力な殺戮能力を実証しました. この研究は,リンパ球細胞毒性中に標的細胞DNAの分解におけるグラン酵素Aの役割を強調しています.

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