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ミトラアヌルスの硬いリング固定は,正常な犬の心臓における左心室シストリック機能を損なわない
S C Rayhill1, L J Castro, M A Nizyporuk
1Department of Cardiovascular and Thoracic Surgery, Stanford University School of Medicine, Calif.
Circulation
|November 11, 1992
まとめ
リジッドミトラアヌロプラスティの固定は左心室 (LV) のシストリック機能を損なわない. この研究では,犬の固定型対移動型ミトラアヌリで,グローバルなまたは地域的なLVメカニズムにおいて有意な変化は見られなかった.
科学分野:
- 心血管生理学 心血管の生理学
- 心臓のメカニズム 心臓のメカニズム
- 手術研究の研究について
背景:
- 以前の研究によると,ミトラアヌロプラスティリングは左心室 (LV) のシストリックパフォーマンスに悪影響を及ぼす可能性がある.
- この研究では,硬いミトラル環状固定がLVのシストリック機能に与える影響を調査しています.
研究 の 目的:
- 厳格なミトラルの環状固定がLVの縮機能を変化させるという仮説を検証する.
- 負荷無感度インデックスを評価するために,グローバルおよびリージョナルのLV収縮力学.
主な方法:
- 硬直に固定され,自由に動けるミトラル・アヌリルを持つ10匹の犬におけるグローバルと地域におけるLVのシストリックメカニズムを比較した.
- Carpentier-Edwardsのアンヌロプラスティリングを使用し,エンドシストリック弾性およびプレロードリクルート可能な脳卒中作業などのパラメータを評価しました.
- 異なるリング条件下で測定された大動脈の流れ,LV圧,およびLV寸法.
主要な成果:
- 厳格に固定された状態と自由に移動するミトラルの環状状態の間の全般的なLVシストリックメカニズムにおいて,有意な差異は観察されなかった.
- 地域的なLVのシストリックパフォーマンスも,硬直なミトラルの環状固定で有意な変化を示さなかった.
- エンド・シストリック室の弾性および繊維の弾性を含む主要なパラメータは変わらなかった.
結論:
- mitra annulusの固い固定は,全体的なLVシストリック機能を変化させない.
- 地域のLVシストリック機能も,硬いミトラリングラ固定によって影響を受けません.
- 発見は,麻酔を施された,正常な心室を持つ,胸を開けた犬に適用されます.
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