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Updated: Jul 23, 2026

The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System
11:27

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Published on: April 25, 2012

単一のアミノ酸の差異は,ヒトとネズミの5-HT1B受容体間の主要な薬理学的変化を与える

D Oksenberg1, S A Marsters, B F O'Dowd

  • 1Department of Pulmonary Research and Gene Therapy, Genentech Inc., South San Francisco, California 94080.

Nature
|November 12, 1992
PubMed
まとめ

単一のアミノ酸の変化が,ヒトとネズミの間の5-ヒドロキシトリプタミン (5-HT) 受容体薬物結合の違いを説明しています. この発見は,ヒトの5-HT1B受容体を確認し,種特有の薬物反応を強調しています.

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