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Updated: Jul 6, 2026

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation

Published on: February 28, 2019

MHCでコードされたプロテアゾームサブユニットは,MHCクラスI分子に結合したペプチドの処理に通常必要とされません

D Arnold1, J Driscoll, M Androlewicz

  • 1Division of Tumor Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115.

Nature
|November 12, 1992
PubMed
まとめ

この研究は,プロテアソームが抗原処理に欠かせないことを示しています. 重要なプロテアソーム成分 (LMP2およびLMP7) を欠いた場合でも,細胞はペプチドを主要な組織適合性複合体のクラスI分子を介して提示することができます.

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