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Updated: Jul 6, 2026

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
09:18

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

BH3のみのタンパク質であるpumaとnoxaによって媒介されるp53-および薬物誘発のアポプトシス反応

Andreas Villunger1, Ewa M Michalak, Leigh Coultas

  • 1Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia. andreas.villunger@uibk.ac.at

Science (New York, N.Y.)
|September 23, 2003
PubMed
まとめ

腫瘍抑制剤p53は,ノクサやプマのような遺伝子を通してアポトーシスを開始します. Puma欠乏症は,細胞をDNA損傷やその他の細胞毒性攻撃から保護し,細胞死における重要な役割を強調しています.

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