固体NMRスペクトロスコーピーの方法,単離された均一にラベル付けされた残留物を持つペプチドにおける脊髄のトルション角度psiを決定する

Jerry C C Chan1, Robert Tycko

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520, USA.

PubMed
まとめ

私たちは,ペプチド骨幹のトルション角度psiを決定するために,新しい固体NMR方法であるROCSA-LGを開発しました. この技術は効率的で,ペプチドとアミロイド線維の均一にラベル付けされた残基を分析するためにわずか5つのスペクトルが必要です.

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