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Updated: Aug 18, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method

Published on: September 16, 2017

合理的に設計された支配的陰性TNF変種によるTNFシグナル伝達の無効化

Paul M Steed1, Malú G Tansey, Jonathan Zalevsky

  • 1Xencor, 111 West Lemon Avenue, Monrovia, CA 91016, USA.

Science (New York, N.Y.)
|September 27, 2003
PubMed
まとめ

科学者は,原生TNFを中和するために,変異性腫瘍死滅因子 (TNF) タンパク質を設計しました. この戦略は,封じ込めによってTNFを無効化し,抗炎症的バイオセラピュティクスの潜在的な新しいアプローチを提供します.

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