ダイアストリックバイブレーションは,不完全なリラックス状態の場合,シストリック機能を改善します
1First Department of Internal Medicine, Tohoku University School of Medicine, Sendai, Japan.
Circulation
|December 1, 1992
まとめ
ダイアストリック振動は,犬の左心室 (LV) のリラクゼーションとシストリック機能を改善しました. この機械的干渉は,脳卒中容量とピークLV圧力を増加させ,下静脈機能不全に対する潜在的な治療方法を示唆した.
科学分野:
- 心血管生理学 心血管の生理学
- バイオメディカルエンジニアリング
- 心臓のメカニズム 心臓のメカニズム
背景:
- 左心室 (LV) のリラクゼーションが不完全である場合,LVの充填が損なわれ,シストリック機能への影響は不明である.
- 静脈動脈機能の強化のための方法を調査することは,心臓のパフォーマンスを改善するために非常に重要です.
研究 の 目的:
- 立方体振動がLVのリラックスを改善できるかどうかを評価する.
- LVシストリック機能に対する強化リラクゼーションの影響を決定する.
主な方法:
- 誘導された不完全なLVのリラックスで開いた胸の10の犬のモデルを使用しました.
- ディアストール中にLV表面に振動性機械的干渉 (ダイアストリック振動) を適用します.
- 様々な条件下で測定された LV 圧力,ストローク 容量,および リラクゼーション パラメータ.
主要な成果:
- ダイアストリック振動は,LV圧力低下の時間常数 (T) を減らし,加速したリラックスを示した.
- ペース式タキカルディアでは,振動がLVピークシストリック圧力と脳卒中量を増加させた.
- 強化されたリラクゼーションは,フランク・スターリングメカニズムを通じて,シストリック機能の改善と相関する.
結論:
- 立方体振動は,LVのリラックス速度を効果的に加速します.
- 改善されたダイアストリックリラクゼーションはシストリック機能を強化し,潜在的な治療戦略を示唆します.
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