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Updated: May 1, 2026

Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair
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Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair

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抗単細胞化学誘導タンパク質-1遺伝子療法は,実験的な心筋梗塞後の左心室リモデリングと不全を弱める

Shunji Hayashidani1, Hiroyuki Tsutsui, Tetsuya Shiomi

  • 1Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Circulation
|October 1, 2003
PubMed
まとめ

モノサイト化学吸引タンパク質-1 (MCP-1) の活性化により,心筋梗塞 (MI) の後の心不全が悪化する. 遺伝子治療でMCP-1を阻害すると,MIのマウスでは生存率が向上し,心臓の改造が減少しました.

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