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Updated: Jul 5, 2026

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
06:21

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

独特の人工転写活性化剤で転写機構を標的にする

Zhiqian Wu1, Garrette Belanger, Brian B Brennan

  • 1Departments of Chemistry and Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

Journal of the American Chemical Society
|October 9, 2003
PubMed
まとめ

研究者らは,遺伝子発現を制御するための新種の人工転写活性化剤を特定し,遺伝子誤調に関連した疾患に対する新たな治療の可能性を提供した. これらの活性化剤は,ユニークな結合特性を発揮し,遺伝子治療の開発の選択肢を拡大しています.

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