HIV感染した男性におけるHemophilus influenzaeの侵入性感染症
R Steinhart1, A L Reingold, F Taylor
1Epidemiology Program, School of Public Health, University of California, Berkeley 94720.
JAMA
|December 16, 1992
まとめ
既得免疫不全症候群 (AIDS) またはヒト免疫不全ウイルス (HIV) 感染の男性では,侵入性ヘモフィルス・インフルーエンサエ病のリスクが高くなります. しかし,これらの感染症は,この集団では,血清型bの場合でも,珍しいままです.
科学分野:
- 感染症 感染症は感染症です.
- 免疫学 免疫学とは
- 公衆衛生は公衆衛生である.
背景:
- 侵襲的なHaemophilus influenzae病は,免疫系が低下した個人にリスクをもたらす.
- H. influenzaeの発生率と血清型の分布を理解することは,公衆衛生戦略にとって極めて重要です.
研究 の 目的:
- エイズまたはHIVに感染した男性における侵入性ヘモフィルス・インフルーエンゼ感染症の発生率を評価する.
- H. influenzae 血清型b.によって引き起こされるこれらの感染症の割合を決定する.
主な方法:
- 集団ベースのアクティブサーベイランスは採用された.
- データはサンフランシスコの保健省によって収集されました.
- この研究では,侵襲的なH.influenzae病を患った20〜49歳の男性が含まれていました.
主要な成果:
- 侵襲性H. influenzae疾患の累積的な発生率は,AIDSの男性では10万人に79.2人,AIDSの男性では10万人に14.6人でした.
- 侵襲的なH.influenzae症例の33%のみがb型血清菌であった.
- H. influenzae bの感染率は,AIDSを患った男性とAIDSを患っていないHIVに感染した男性で,それぞれ10万人に11.3と7.6であった.
結論:
- エイズやHIV感染を患っている男性は,侵入性H. influenzae感染のリスクが高くなります.
- 増加したリスクにもかかわらず,血清型bを含む侵襲的なH. influenzae感染症は,この人口集団ではまれです.
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