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ST上昇急性心筋梗塞におけるシロリマス放出ステントの埋め込み:臨床および血管学的研究
Francesco Saia1, Pedro A Lemos, Chi-Hang Lee
1Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Circulation
|October 15, 2003
まとめ
シロリムス放出ステント (SES) は,ST上昇の急性心筋梗塞の患者にとって安全であり,6ヶ月でレステノシスを示さない. この研究では,96人の患者にSESインプラントを評価し,不良心疾患の減少に有効であることが判明しました.
科学分野:
- 心臓病学 心臓病学
- 介入性心臓病学 介入性心臓病学
- バイオメディカルエンジニアリング
背景:
- シロリムス放出ステント (SES) は,裸のステントと比較してレステノスを軽減します.
- 急性心筋梗塞 (AMI) におけるSESの安全性と有効性は,以前は知られていなかった.
研究 の 目的:
- STエレベーション急性心筋梗塞 (STEMI) 患者におけるSESインプラントの安全性と有効性を評価する.
主な方法:
- RESEARCHのレジストリでは,STEMI患者に対して,SESのルーチンインプラントの方針が制定されました.
- STEMIの96人の患者は,SESインプランテーションによる皮膚経冠動脈介入を受けた.
- 主要な不良心事および血管検査の追跡は6ヶ月後に評価された.
主要な成果:
- 術後のTIMI-3フローは,患者の93.3%で達成されました.
- 病院での死亡率は6.2%で,早期再発症と再介入が1回あった.
- 6ヶ月のフォローアップで,再発性心筋梗塞,死亡,または追加の再介入を経験した患者はいなかった. ステントの血栓症は記録されていません.
- 患者の70%の血管図による追跡調査では,レステノシスがないことと,遅い損失が最小 (-0.04+/-0.25) であることを示した.
結論:
- シロリムス放出ステントの埋め込みは,STEMI患者にとって安全な戦略です.
- このSTEMIコホートでは,SESのインプラント化により,6ヶ月後に血管図学的レステノーシスがないことが示されました.
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