ストレス誘発性胸痛の患者における血中酸素レベル依存磁気共鳴画像検査
Matthias G Friedrich1, Thoralf Niendorf, Jeanette Schulz-Menger
1Helios-Klinikum Berlin, Franz-Volhard-Klinik, Kardiologie Charité Campus Berlin-Buch, Medizinische Fakultaet der Humboldt-Universitaet Berlin, Germany. friedrich@fvk-berlin.de
Circulation
|October 15, 2003
まとめ
血液中の酸素レベルに依存した (BOLD) MRIは,冠動脈疾患の疑いのある患者の心筋不全を検出することができます. このテクニックは,ストレス誘発性アンギナを引き起こす重度の冠動脈狭窄症を特定する有望なことを示しています.
科学分野:
- 心血管画像検査についてです.
- 医療診断 医療診断
- 生理学 生理学とは
背景:
- 血中酸素レベル依存 (BOLD) マグネット共鳴画像 (MRI) は,組織の酸素化を評価する.
- BOLD MRIは,冠動脈疾患の疑いのある患者の心筋梗塞不全の検出に役立ちます.
研究 の 目的:
- アデノシン誘発BOLDMRIの有用性を評価し,心筋不全を特定する.
- ストレス誘発性アンギナを持つ患者の冠動脈血管図とSPECTとのBOLD MRIの結果と相関する.
主な方法:
- T2*センシティブのエコープラナー画像シーケンスが,ストレス誘発性胸痛の患者25人に使用されました.
- BOLD MRIは,アデノシン投与前およびその間に行われました.
- 結果は,定量アンジオグラフィーとアデノシンタリウム単光子放出コンピューティングトモグラフィー (SPECT) と比較されました.
主要な成果:
- アデノシン中に冠動脈狭窄症 >75%の心筋細節で平均信号強度の低下が観察されました.
- BOLD MRIは88%の感度と47%の特異性を示し,重度の狭窄症を分類しました.
- SPECTとの相関は,実質的な変動を示しました.
結論:
- アデノシン・ボールド・MRIは,重度の冠動脈狭窄症に関連した部分における心筋不全を効果的に検出します.
- 空間的カバーと画像品質のさらなる改善は,診断の可能性を高める可能性があります.
関連する概念動画
Angina III: Clinical Manifestations and Assessment
Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Imaging Studies for Cardiovascular System IV: CMRI
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Acute Coronary Syndrome III: Diagnostic Studies
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Angina V: Nursing Management
Angina, a symptom of myocardial ischemia, requires a structured nursing management approach to ensure effective care and prevent complications like myocardial infarction. Comprehensive nursing care involves assessing, diagnosing, planning, implementing interventions, and evaluating outcomes, all tailored to the individual patient's needs.Patient AssessmentNursing assessment begins with a detailed subjective evaluation of symptoms, which typically include chest pain or pressure radiating to the...
Exercise Stress Test
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes

