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Updated: Jul 18, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

血液形成細胞の調節は,Rac1とRac2のグアノシントリフォスファタゼによって行われます

Yi Gu1, Marie-Dominique Filippi, Jose A Cancelas

  • 1Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

Science (New York, N.Y.)
|October 18, 2003
PubMed
まとめ

ロー・グアノシン・トリフォスファタゼ (GTPases) Rac1とRac2は,血液形成幹細胞にとって不可欠である. Rac1とRac2の両方を削除すると,細胞の脱出が起こりますが,Rac1欠乏だけが骨髄移植を阻害します.

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