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Updated: Jul 13, 2026

Interview: HIV-1 Proviral DNA Excision Using an Evolved Recombinase
10:20

Interview: HIV-1 Proviral DNA Excision Using an Evolved Recombinase

Published on: June 16, 2008

HIV-1 Vif-Cul5-SCF複合体によるAPOBEC3Gのユビキチン化と分解の誘導

Xianghui Yu1, Yunkai Yu, Bindong Liu

  • 1Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|October 18, 2003
PubMed
まとめ

ヒト免疫不全ウイルス-1 (HIV-1) Vifタンパク質は,細胞Cul5-SCF複合体を用いて,抗ウイルス因子APOBEC3Gを分解する. この相互作用は,ウイルスの回避に極めて重要であり,新しいHIV治療法の開発の潜在的なターゲットです.

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Amplification of Near Full-length HIV-1 Proviruses for Next-Generation Sequencing

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