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Updated: Jul 23, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

BRCA1およびBRCA2の遺伝性突然変異による乳がんおよび卵巣がんのリスク

Mary-Claire King1, Joan H Marks, Jessica B Mandell

  • 1Departments of Medicine and Genome Sciences, University of Washington, Seattle, WA 98195, USA. mcking@u.washington.edu

Science (New York, N.Y.)
|October 25, 2003
PubMed
まとめ

BRCA1/BRCA2変異を持つアシュケナジ・ユダヤ人女性は,乳がん (82%) と卵巣がん (54%のBRCA1,23%のBRCA2) の生涯リスクが高い. 運動などのライフスタイルの要因は,乳がんの発症を遅らせる可能性があります.

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