Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Pulse amplitude and quality01:17

Pulse amplitude and quality

3.7K
Pulse amplitude is a crucial indicator of cardiac health because it provides valuable insights into the strength of left ventricular contractions and the overall uniformity of blood circulation within the vasculature. The strength of the pulse is directly related to the force with which the heart contracts and the volume of blood being pumped.
A weak or absent pulse may indicate reduced cardiac output or poor left ventricular contraction, which can be signs of cardiovascular dysfunction or...
3.7K
Stress-Strain Diagram - Brittle Materials01:24

Stress-Strain Diagram - Brittle Materials

4.6K
Brittle materials, including glass, cast iron, and stone, exhibit unique characteristics. They fracture without considerable change in their elongation rate, indicating that their breaking and ultimate strength are equivalent. Such materials also show lower strain levels at the point of rupture. The failure in brittle materials predominantly results from normal stresses, as evidenced by the rupture created along a surface perpendicular to the applied load. These materials do not display...
4.6K
Cardiovascular System Abnormal Findings I: Inspection and Palpation01:29

Cardiovascular System Abnormal Findings I: Inspection and Palpation

1.3K
In a cardiovascular examination, inspection and palpation are crucial for identifying abnormalities.
Abnormal findings observed during an inspection
1.3K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

1.1K
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
1.1K
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

2.5K
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
2.5K
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

663
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
663

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Assessment of modifications to a blind-sweep ultrasound protocol for improved lower-uterus imaging by novice operators.

Scientific reports·2026
Same author

Monitoring <i>in vitro</i> gastric bolus digestion with ultrasound.

Food & function·2026
Same author

Frequency and mutual associations of knee osteoarthritis features on ultrasound imaging in recent-onset symptomatic knee osteoarthritis patients: A cross-sectional analysis in a convenience sample of Dutch patients.

Osteoarthritis and cartilage open·2026
Same author

Cascaded Plane Wave Ultrasound Velocity Vector Imaging: In Vivo Feasibility in Carotid Arteries.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2025
Same author

Proof of concept 3D ultrasound strain imaging measuring effect of a ring pessary on avulsed puborectal muscle.

Communications medicine·2025
Same author

Artificial intelligence assisted ultrasound for selective screening of hip dysplasia at children's health care centers in the Netherlands.

Computer methods and programs in biomedicine·2025

関連する実験動画

Updated: May 6, 2026

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
09:43

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis

Published on: August 4, 2011

17.5K

血管内弾性エラストグラフィによる脆弱なプラークの特徴の特徴づけ

Johannes A Schaar1, Chris L De Korte, Frits Mastik

  • 1Thoraxcenter Erasmus MC Rotterdam, Kamer Ee 23.32, PO Box 1738, 3000 DR Rotterdam, The Netherlands. j.schaar@erasmusmc.nl

Circulation
|October 29, 2003
PubMed
まとめ
この要約は機械生成です。

血管内エラストグラフィは,心血管疾患の診断の重要なステップである脆弱なプラークを特定する上で高い精度を示しています. このテクニックは,薄いキャップのアテロマを検出することができ,患者のリスクの階層化を改善します.

さらに関連する動画

A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue
13:45

A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

Published on: November 11, 2022

3.7K
Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
06:18

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

1.2K

関連する実験動画

Last Updated: May 6, 2026

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis
09:43

In vivo Near Infrared Fluorescence NIRF Intravascular Molecular Imaging of Inflammatory Plaque, a Multimodal Approach to Imaging of Atherosclerosis

Published on: August 4, 2011

17.5K
A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue
13:45

A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue

Published on: November 11, 2022

3.7K
Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
06:18

Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

Published on: December 6, 2024

1.2K

科学分野:

  • 心血管画像検査についてです.
  • バイオメディカルエンジニアリング
  • 病理学 パトロジー

背景:

  • 脆弱なプラークのインビオ検出は,現在の診断ツールによって制限されています.
  • 血管内超音波エラストグラフィー (IVUS-E) は,プラークのフェノタイプを区別する可能性があることを示しています.
  • 脆弱なプラークの検出に対するIVUS-Eの予測価値は,以前は研究されていなかった.

研究 の 目的:

  • 脆弱なプラークを検出するための血管内弾性エラストグラフィの予測価値を評価する.
  • エラストグラフィの発見とプラークの脆弱性の組織学的特徴を相関させる.

主な方法:

  • 死後の冠動脈は,血管内弾性図と組織学を用いて分析された.
  • 脆弱なプラークは,組織学的に薄いキャップ (<250μm),マクロファージの浸透,およびアテロマの含有量によって定義されました.
  • エラストグラフィーは,特定のストレングパターン (高表面,隣接する低ストレング地域) によって脆弱なプラークを定義しました.

主要な成果:

  • 24の冠動脈からの54の横断面の分析により,26の脆弱性および28の非脆弱性プラークが特定されました.
  • 血管内エラストグラフィーは,脆弱なプラークを検出するための88%の感度と89%の特異性を示しました.
  • 1.26%のストレイン値の値で,最も高い予測力 (AUC=0.85) が得られました.
  • エラストグラフィーの発見は,キャップの厚さ,マクロファージの浸透,および滑らかな筋肉細胞の含有量と有意に相関していました.

結論:

  • 血管内弾性エラストグラフィーは,脆弱なプラークを検出するための非常に敏感で特定の方法です.
  • このテクニックは,プラークの脆弱性のインビトロ評価において有望であることが示されています.
  • IVUS-Eの発見は,プラークの不安定性の主要な組織学的マーカーと相関しています.