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Updated: Jul 5, 2026

Interview: Protein Folding and Studies of Neurodegenerative Diseases
19:50

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パーキンソン病における神経変性の分子経路

Ted M Dawson1, Valina L Dawson

  • 1Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. tdawson@jhmi.edu

Science (New York, N.Y.)
|November 1, 2003
PubMed
まとめ

パーキンソン病 (PD) は,ミトコンドリア複合体Iの阻害から生じ,アルファ-シヌクレインの集積とドーパミンニューロンの死につながる可能性があります. 複合体I,酸化ストレス,タンパク質処理を標的とした治療法は,PDにおける神経保護の有望性を示しています.

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