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Updated: Apr 19, 2026

Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope
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Imaging of Estrogen Receptor-α in Rat Pial Arterioles using a Digital Immunofluorescent Microscope

Published on: November 29, 2011

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エストロゲン受容体アルファ遺伝子変異と心血管疾患との関連

Amanda M Shearman1, L Adrienne Cupples, Serkalem Demissie

  • 1Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Mass 02139, USA. shearman@mit.edu

JAMA
|November 6, 2003
PubMed
まとめ

一般的なESR1c.454-397CC遺伝子型は,心筋梗塞 (MI) と大動脈硬化性心血管疾患 (CVD) のリスクを大幅に増加させます. この遺伝的変異は,特に男性におけるCVD感受性におけるエストロゲン受容体の役割を強調しています.

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