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Updated: Jun 26, 2026

Efficient and Cost Effective Electroporation Method to Study Primary Cilium-Dependent Signaling Pathways in the Granule Cell Precursor
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ネズミのヘッジホッグシグナル伝達には,フラゲル内輸送タンパク質が必要です

Danwei Huangfu1, Aimin Liu, Andrew S Rakeman

  • 1Developmental Biology Program, Sloan-Kettering Institute, 1275 York Avenue, New York, New York 10021, USA.

Nature
|November 7, 2003
PubMed
まとめ

イントラフラジェラトランスポート (IFT) タンパク質は,脊椎動物の発達におけるソニック・ヘッジホッグ (Hedgehog) 信号伝達に不可欠です. この研究は,IFTタンパク質に影響を与える新しいマウス変異体を特定し,胚のパターニングとヘッジホッグ信号伝導におけるそれらの重要な役割を明らかにしています.

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