APLは,アラビドopsisの血管組織のアイデンティティを調節する
Martin Bonke1, Siripong Thitamadee, Ari Pekka Mähönen
1Plant Molecular Biology Laboratory, Institute of Biotechnology, POB 56, FIN-00014, University of Helsinki, Finland.
Nature
|November 14, 2003
まとめ
研究者らは,アラビドopsis. inのフロームのアイデンティティに決定的なALTERED PHLOEM DEVELOPMENT (APL) 遺伝子を特定しました. この遺伝子はフロームの分化を促進しながら,キシレムの発達を阻害し,血管組織のパターンを明確にします.
科学分野:
- 植物生物学 植物生物学
- 分子遺伝学 分子遺伝学
- 発達生物学 発達生物学とは
背景:
- 血管系植物は,長距離輸送のためにフロームとキシレムを使用します.
- フロエムは,シート要素と相棒細胞で構成され,キシレムは,線性化された気管要素を含みます.
- フローム-キシレムパターンの遺伝的コントロールは,ほとんど知られていなかった.
研究 の 目的:
- アラビドプシスのフローム-キシレムパターンを制御する遺伝子を特定するために.
- ALTERED PHLOEM DEVELOPMENT (APL) 遺伝子の機能を明らかにするために.
主な方法:
- アラビドプシスの変異体の遺伝子解析.
- APLの遺伝子発現プロファイリング.
- エクトピックAPL発現の分析.
主要な成果:
- ALTERED PHLOEM DEVELOPMENT (APL) 遺伝子は,フロームの同一性にとって不可欠である.
- リセッシブなAPL変異はフロームの発達を妨げ,フロームの位置にキセラムのような細胞をもたらします.
- APLの発現は,発育中のフロームに局限しています.
- エクトピックAPL発現は,キシレムの発達を阻害する.
結論:
- APLは,血管の発達を調節するMYB転写因子として作用する.
- APLはフロームの分化を促進し,キシレムの分化を抑制する.
- APLは,フローム-キシレムパターンを確立する上で二重の役割を果たします.
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