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Updated: Jul 11, 2026

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CREBは,核ホルモン受容体PPAR-ガンマを通して,肝臓の脂質代謝を制御する

Stephan Herzig1, Susan Hedrick, Ianessa Morantte

  • 1Peptide Biology Laboratories Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, California 92037-1002, USA.

Nature
|November 14, 2003
PubMed
まとめ

断食は,HES-1経由でPPAR-gammaを抑制するCREBを活性化することによって脂肪合成を抑制します. このメカニズムは,断食中の肝臓脂肪の調節を説明し,インスリン感受性の治療目標を示唆しています.

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