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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
11:44

Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities

Published on: October 2, 2018

ジムノシン-Aの全合成

Chihiro Tsukano1, Makoto Sasaki

  • 1Laboratory of Biostructural Chemistry, Graduate School of Life Sciences, Tohoku University, Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan.

Journal of the American Chemical Society
|November 20, 2003
PubMed
まとめ

研究者は,細胞毒性のある海洋天然産物であるジムノシンAの全合成を達成しました. 重要なステップには,鈴木・ミヤウラ結合と,この複雑な分子のためのステレオセレクティブヒドロキシル群の導入が含まれています.

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