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Updated: Jul 15, 2026

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
11:08

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli

Published on: December 9, 2017

モジュラーポリケチド合成酵素のモジュール性の強化:モジュラーポリケチド合成酵素におけるトランサイレーションは,マロニル-CoA:ACPトランサイラゼによって触媒化された

Pawan Kumar1, Andrew T Koppisch, David E Cane

  • 1Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.

Journal of the American Chemical Society
|November 20, 2003
PubMed
まとめ

研究者らは,アシルトランスファーゼ (AT) ドメインを改変することによって,モジュラーポリケチド合成酵素を設計した. この戦略により,拡張装置の組み込みを正確に制御することができ,新しいポリケチド天然製品アナログの合成が可能になります.

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