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Updated: May 5, 2026

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
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Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

Published on: December 8, 2013

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サイクロオキシゲネーゼイソフォームと血小板血管壁の相互作用は,アテロスクレロシスのアポリプロテインEノックアウトマウスモデルにおける

Orina A Belton1, Angela Duffy, Sinead Toomey

  • 1Department of Clinical Pharmacology and Institute of Biopharmaceutical Sciences, Royal College of Surgeons in Ireland 123, St Stephens Green, Dublin 2, Ireland. obelton@rcsi.ie

Circulation
|November 26, 2003
PubMed
まとめ

サイクロオキシゲネーゼ-1 (COX-1) は,動脈硬化症における早期の病変形成を予防する上で極めて重要です. COX-1を阻害すると,病変の発生が減少し,COX-2を阻害すると,動脈硬化症の進行や血小板活性に影響はなかった.

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