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Updated: Jul 18, 2026

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling
10:49

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

Published on: September 20, 2016

癌細胞におけるアポトーシスを選択的に誘導する小分子の組み合わせ図書庫からの識別

Vitaliy Nesterenko1, Karson S Putt, Paul J Hergenrother

  • 1Department of Chemistry, Roger Adams Laboratory, University of Illinois, Urbana, IL 61801, USA.

Journal of the American Chemical Society
|December 4, 2003
PubMed
まとめ

研究者は,がん細胞のアポトーシス誘発剤を見つけるために88の化合物のライブラリを合成しました. ある化合物は,健康な白血球を傷つけることなく,がん細胞のプログラム細胞死を選択的に誘発する (U-937,HL-60).

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