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Updated: May 5, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
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薬理学:エクスタシーから苦痛を切り離す

Edward M Mills1, Matthew L Banks, Jon E Sprague

  • 1Cardiovascular Branch, NHLBI, National Institutes of Health, Bethesda, Maryland 20892-1622, USA.

Nature
|December 4, 2003
PubMed
まとめ

ミトコンドリアタンパク質UCP-3 (解離タンパク質-3) が欠けているマウスは,MDMA (エクスタシー) から体温上昇が低下したことを示した. これは,UCP-3がMDMA誘発性高温症において重要な役割を果たし,潜在的な治療目標を提供することを示唆しています.

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