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Updated: Jun 25, 2026

A Strategy to Identify Compounds that Affect Cell Growth and Survival in Cultured Mammalian Cells at Low-to-Moderate Throughput
12:22

A Strategy to Identify Compounds that Affect Cell Growth and Survival in Cultured Mammalian Cells at Low-to-Moderate Throughput

Published on: September 22, 2019

TSC2は細胞の成長と生存を制御するために細胞のエネルギー反応を媒介する

Ken Inoki1, Tianqing Zhu, Kun-Liang Guan

  • 1Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

Cell
|December 4, 2003
PubMed
まとめ

結核性硬化症複合体は,TSC1/TSC2遺伝子変異と関連しています. 新しい発見は,TSC2が細胞のエネルギー反応を調節し,AMPKのリン酸化が細胞をエネルギー欠乏とアポトーシスから保護することを示しています.

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