敵対的な行動は,多重リスク因子介入試験に登録された男性の心血管疾患による死亡率を予測します
Karen A Matthews1, Brooks B Gump, Kelly F Harris
1University of Pittsburgh, 3811 O'Hara St, Pittsburgh, Pa 15213, USA. matthewska@upmc.edu
Circulation
|December 10, 2003
まとめ
敵意は,高リスクの男性における心血管疾患 (CVD) 死亡率と関連しています. 高度の敵意,特に非致命的なCVDイベントの後に,CVDで死亡するリスクを大幅に増加させます.
科学分野:
- 心臓病学 心臓病学
- 心理社会的要因 心理社会的要因
- 公衆衛生は公衆衛生である.
背景:
- 敵意は冠動脈疾患の既知の危険因子である.
- 高リスク集団における心血管疾患 (CVD) 死亡率との関連は,まだ十分に研究されていない.
研究 の 目的:
- 多重リスク因子介入試験 (MRFIT) の参加者における16年以上の敵対心とCVD死亡率の関連性を評価する.
- 試験中に非致命的なCVDイベントを経験した男性におけるCVD死亡率に対する敵意の影響を調査する.
主な方法:
- 構造面接の回答から,人際的敵意評価技術を用いて敵意を評価した.
- CVDで死亡した259人の男性と259人の対照群のデータを分析した.
- 血圧,コレステロール,喫煙,および前述の非致命的なCVDイベントを含む共変数に制御されています.
主要な成果:
- 高い敵意を持つ男性は,CVD死亡率 (OR,1.61;95%CI,1.092.39) の可能性が著しく高いことを示しました.
- CVDの死亡リスクは,試験中に非致命的なCVDイベントを経験した高敵対性の男性において特に高かった (OR,5.06;95%CI,1.428.22).
結論:
- 敵意は,高リスクの男性における心血管疾患による死亡率の重要な危険因子である可能性があります.
- 怒りの管理とストレスの軽減に焦点を当てた介入は,従来のリスク因子修正と並行して,敵対的な患者に利益をもたらす可能性があります.
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