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Updated: Jun 21, 2026

Delivery of Proteins, Peptides or Cell-impermeable Small Molecules into Live Cells by Incubation with the Endosomolytic Reagent dfTAT
10:30

Delivery of Proteins, Peptides or Cell-impermeable Small Molecules into Live Cells by Incubation with the Endosomolytic Reagent dfTAT

Published on: September 2, 2015

致命的な方法でタンパク質を折りたたむ

Dennis J Selkoe1

  • 1Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. dselkoe@rics.bwh.harvard.edu

Nature
|December 20, 2003
PubMed
まとめ

タンパク質の誤折り合いは,不溶性堆積を引き起こし,アルツハイマー病やパーキンソン病などの神経退行性疾患を引き起こす. タンパク質の折り畳みを理解することは,これらの困難なアミロイドーシス疾患に対する新しい治療戦略を提供します.

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