関連する実験動画

Updated: May 3, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

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固有のアデニル酸キナーゼ活性が,ABCトランスポーターCFTRのゲート化を調節する

Christoph Randak1, Michael J Welsh

  • 1Howard Hughes Medical Institute, Department of Internal Medicine and Physiology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

Cell
|December 31, 2003
PubMed
まとめ

システィック・フィブロシス・トランスメブラン・コンダクトンス・レギュレータ (CFTR) タンパク質は,ATPアゼとアデニラートキナーゼの両方として作用し,二重の酵素活性を持っています. この二重機能,特にアデニル酸キナーゼ活性により,最小限のエネルギー消費でCFTRチャネルゲーティングを調節することができる.

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