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Updated: Jul 17, 2026

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
09:13

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy

Published on: November 1, 2011

nef遺伝子のデリエーションを伴う生体弱化SIVワクチンによる保護効果

M D Daniel1, F Kirchhoff, S C Czajak

  • 1New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772.

Science (New York, N.Y.)
|December 18, 1992
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) に対するワクチンの開発は困難です. 研究者らは,猿の免疫不全ウイルス (SIV) からNEF遺伝子を削除することで,サルを病原性SIVから保護する安全で活体弱化ワクチンが作成されたことを発見しました.

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Peptide-based Identification of Functional Motifs and their Binding Partners

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Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques13:13

Single-cell Quantitation of mRNA and Surface Protein Expression in Simian Immunodeficiency Virus-infected CD4+ T Cells Isolated from Rhesus macaques

Published on: September 25, 2018

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