酵母における未結合mRNAの核保持は,周核Mlp1によって媒介される

Vincent Galy1, Olivier Gadal, Micheline Fromont-Racine

  • 1Unité de Biologie Cellulaire du Noyau, CNRS URA 2582, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.

Cell
|January 14, 2004
PubMed
まとめ

イーストにおけるイントロンを含むmRNAの核保持は,周核Mlp1タンパク質によって媒介されます. MLP1を削除すると,保持が減少し,Mlp1がmRNAの輸出のための核品質管理メカニズムとして機能することを示唆します.

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