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Updated: Jun 25, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

SRPのヘテロディメア型GTPアゼ核は,複合体をターゲットにしています

Pamela J Focia1, Irina V Shepotinovskaya, James A Seidler

  • 1Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611, USA.

Science (New York, N.Y.)
|January 17, 2004
PubMed
まとめ

FfhとFtsYの2つの同類のグアノシントリフォスファターゼ (GTPase) ドメインがヘテロダイマーを形成し,タンパク質を標的とする分子ラッチ機構を明らかにします. この構造は,膜タンパク質の組立中にGTPaseの活性化とアロステリックシグナル伝達を説明する.

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Comparing the Affinity of GTPase-binding Proteins using Competition Assays10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

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ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast07:31

ACT1-CUP1 Assays Determine the Substrate-Specific Sensitivities of Spliceosomal Mutants in Budding Yeast

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