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Updated: Jul 5, 2026

Spheroid Assay to Measure TGF-β-induced Invasion
09:18

Spheroid Assay to Measure TGF-β-induced Invasion

Published on: November 16, 2011

線維芽細胞におけるTGF-βシグナル伝達は,隣接する上皮質の腫瘍発生可能性を調節する

Neil A Bhowmick1, Anna Chytil, David Plieth

  • 1Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Science (New York, N.Y.)
|February 7, 2004
PubMed
まとめ

線維芽細胞における成長因子β (TGF-β) 信号変換は,近くの上皮組織における癌の発生に影響する. このシグナル伝達を妨害すると,上皮細胞の成長と腫瘍形成が促進され,癌の進行におけるその役割が強調されます.

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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells06:54

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