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Updated: Mar 15, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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VKORC1の変異は,ワルファリン耐性および2型多発凝固因子欠乏症を引き起こす

Simone Rost1, Andreas Fregin, Vytautas Ivaskevicius

  • 1Department of Human Genetics, University of Würzburg, Biozentrum, Am Hubland, 97074 Würzburg, Germany.

Nature
|February 7, 2004
PubMed
まとめ

研究者らは,血液凝固とワルファリン薬の機能に不可欠なビタミンKエポキシドリドゥクタゼ複合体のサブユニット1 (VKORC1) 遺伝子を特定しました. VKORC1の変異は,出血障害とワーファリン耐性に関連しています.

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