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脱リン酸化SRp38は,熱ショックへの反応として,スプライシング抑制剤として作用する

Chanseok Shin1, Ying Feng, James L Manley

  • 1Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

Nature
|February 7, 2004
PubMed
まとめ

熱ショックにより,SRp38タンパク質の脱酸化によってRNAのスプライシングが抑制されます. このストレス反応メカニズムは,SRp38がスプライシング機構を阻害するので,細胞生存に不可欠です.

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