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Updated: Jul 19, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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NF-kappaB抑制体Foxj1によるTh1活性化および炎症の調節

Ling Lin1, Melanie S Spoor, Andrea J Gerth

  • 1Division of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110, USA.

Science (New York, N.Y.)
|February 14, 2004
PubMed
まとめ

転写因子Foxj1はT細胞の活性化を調節し,自己免疫性炎症を予防する. Foxj1の欠乏は,NF-kappaBのシグナル伝達に影響を与えることで,T細胞活動の増加と全身性炎症を引き起こす.

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