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Updated: May 3, 2026

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
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圧力誘発マトリックスメタルプロテインアゼ-9は,早期高血圧の再構築に寄与する

Stéphanie Lehoux1, Catherine A Lemarié, Bruno Esposito

  • 1INSERM U541, Hôpital Lariboisière, 41 boulevard de la Chapelle, 75010 Paris, France. lehoux@larib.inserm.fr

Circulation
|February 18, 2004
PubMed
まとめ

高血圧は,マトリックス金属タンパク質酵素 (MMPs) を活性化することによって,血管構造を変化させます. MMP-9は,早期の高血圧性血管改造と血管の伸縮性に不可欠です.

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