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Updated: Apr 13, 2026

Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq
09:08

Mapping Genome-wide Accessible Chromatin in Primary Human T Lymphocytes by ATAC-Seq

Published on: November 13, 2017

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ヒト染色体21と22に沿った転写因子結合部位の公平なマッピングは,非コーディングRNAsの広範な調節を指しています

Simon Cawley1, Stefan Bekiranov, Huck H Ng

  • 1Affymetrix, 3380 Central Expressway, Santa Clara, CA 95051, USA.

Cell
|February 26, 2004
PubMed
まとめ

この研究では,ヒトゲノム内の転写因子結合部位 (TFBS) をマッピングし,Sp1,cMyc,p53.3の数千の部位を明らかにしました. 多くのTFBSは,コード化しないRNAを調節し,調整された遺伝子調節を示唆しています.

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