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Updated: May 9, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
08:35

Examining BCL-2 Family Function with Large Unilamellar Vesicles

Published on: October 5, 2012

核孤児受容体Nur77/TR3との相互作用により,Bcl-2の保護者からキラーへの変換

Bingzhen Lin1, Siva Kumar Kolluri, Feng Lin

  • 1The Burnham Institute, Cancer Center, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|February 26, 2004
PubMed
まとめ

既知のアポトーシス阻害剤であるBcl-2タンパク質は,Nur77核受容体と相互作用することで,癌細胞の死を促進することができます. この相互作用により,Bcl-2は細胞キラーに変換され,新たな治療戦略が提供されます.

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